Shares of Pfizer Inc. and other biotech drug makers with exposure to COVID treatments fell in the extended session Friday after Pfizer slashed its full-year outlook due to weaker demand for the Paxlovid pill and more.

The company forecast full-year earnings of $1.45 to $1.65 a share on revenue of $58 billion to $61 billion. And Pfizer said guidance calls for a reduction in expected revenue for COVID treatment Paxlovid of $7 billion. It further foresees a $2 billion reduction in revenue for the Comirnaty COVID vaccine it makes with BioNTech
BNTX,
-4.89%
.
Pfizer will have to take a $5.5 billion charge for COVID-product inventory write-offs.

Analysts surveyed by FactSet had expect full-year earnings of $3.29 a share on revenue of $65.96 billion.

Pfizer
PFE,
-2.46%

shares dropped more than 7% after hours, following a 2.5% decline to close the regular session at $32.11. Shares of the Dow Jones Industrial Average component are down more than 37% year to date, while the Dow itself
DJIA
is up 1.6%, and the S&P 500 index
SPX
is up 12.7%.

In August, Pfizer stock came under fire when the drug maker reported a drop in earnings because of weaker demand for COVID vaccines and antiviral drugs. Back then, Pfizer forecast full-year earnings of $3.25 to $3.45 a share on revenue of $67 billion to $70 billion.

The news had a far-reaching effect. Shares of BioNTech declined 1.5% after hours, following a 4.9% fall to close Friday at $103.58.

Shares of Moderna Inc.
MRNA,
-2.46%

and Novavax Inc.
NVAX,
-5.37%

also dropped in the extended session following Pfizer’s announcement. Moderna shares fell more than 4% after hours, following a 2.5% decline to close Friday at $98.30, and Novavax shares fell 2.5%, following a 5.4% drop to close at $7.05.

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